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Endozepines

Archive ouverte | Tonon, Marie-Christine | CCSD

International audience. The existence of specific binding sites for benzodiazepines has led to the discovery of endogenous ligands for benzodiazepine recep-tors that are collectively designated by the term endozepin...

Beta-amyloid peptides stimulate endozepine biosynthesis in cultured rat astrocytes

Archive ouverte | Tokay, Tursonjan | CCSD

International audience. Accumulation of beta-amyloid peptide (Abeta), which is a landmark of Alzheimer's disease, may alter astrocyte functions before any visible symptoms of the disease occur. Here, we examined the...

PACAP Stimulates Biosynthesis and Release of Endozepines from Rat Astrocytes

Archive ouverte | Masmoudi-Kouki, Olfa | CCSD

International audience. Astrocytes synthesize and release endozepines, a family of neuropeptides related to diazepam-binding inhibitor (DBI). Astroglial cells also express the receptors of pituitary adenylate cyclas...

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