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Radiation dosimetry of [ 131 I]ICF01012 in rabbits: Application to targeted radionuclide therapy for human melanoma treatment

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Jouberton, Elodie | Perrot, Yann | Dirat, Béatrice | Billoux, Tommy | Auzeloux, Philippe | Cachin, Florent | Chezal, Jean-Michel | Filaire, Marc | Labarre, Pierre | Miot-Noirault, Elisabeth | Millardet, Corinne | Valla, Clémence | Vidal, Aurélien | Degoul, Françoise | Maigne, Lydia

Edité par CCSD ; American Association of Physicists in Medicine -

International audience. Dosimetry for melanoma-targeted radionuclide therapy (TRT) with [131 I]ICF01012, a melanin ligand, has been previously evaluated in mice bearing melanomas. In this study, activity distribution and dosimetry are performed on healthy rabbits (Fauve de Bourgogne) using SPECT-CT imaging and ex vivo measurements.

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