Afficher la couverture 'Analysis of interaction between telomeric i-motif DNA and a cyclic tetraoxazole compound | Masoud, Shadi Sedghi' en grand format
/5

0 avis

Analysis of interaction between telomeric i-motif DNA and a cyclic tetraoxazole compound

Archive ouverte

Masoud, Shadi Sedghi | Yamaoki, Yudai | Ma, Yue | Marchand, Adrien | Winnerdy, Fernando Richtia | Gabelica, Valérie | Phan, Anh, Tuân | Katahira, Masato | Nagasawa, Kazuo

Edité par CCSD ; Wiley-VCH Verlag -

International audience. The interaction of a macrocyclic tetraoxazole compound, L2H2‐4OTD (1), with two aminoalkyl side chains and telomeric i‐motif, was investigated by means of electrophoretic mobility shift assay, circular dichroism spectroscopy, mass spectrometry and NMR spectroscopy analyses. The results indicate that 1 interacts with the i‐motif structure at two preferred binding sites.

Suggestions

Du même auteur

Differential diagnosis of vitamin D‐related hypercalcemia using serum vitamin D metabolite profiling

Archive ouverte | Kaufmann, Martin | CCSD

International audience. Genetic causes of vitamin D-related hypercalcemia are known to involve mutation of 25-hydroxyvitamin D-24-hydroxylase CYP24A1 or the sodium phosphate co-transporter SLC34A1; which result in e...

Synthesis and Telomeric G-Quadruplex-Stabilizing Ability of Macrocyclic Hexaoxazoles Bearing Three Side Chains

Archive ouverte | Ma, Yue | CCSD

International audience

Unprecedented hour-long residence time of a cation in a left-handed G-quadruplex

Archive ouverte | Winnerdy, Fernaldo Richtia | CCSD

International audience. An extremely long-lived cation has been detected in left-handed G-quadruplexes.

Chargement des enrichissements...