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Calcium signaling mediates a biphasic mechanoadaptive response of endothelial cells to cyclic mechanical stretch

Archive ouverte | Miroshnikova, Yekaterina | CCSD

International audience. The vascular system is precisely regulated to adjust blood flow to organismal demand, thereby guaranteeing adequate perfusion under varying physiological conditions. Mechanical forces, such a...

Force propagation between epithelial cells depends on active coupling and mechano-structural polarization

Archive ouverte | Ruppel, Artur | CCSD

Abstract Cell-generated forces play a major role in coordinating the large-scale behavior of cell assemblies, in particular during development, wound healing and cancer. Mechanical signals propagate faster than biochemical signals...

Centrosome–nuclear axis repositioning drives the assembly of a bipolar spindle scaffold to ensure mitotic fidelity

Archive ouverte | Nunes, Vanessa | CCSD

International audience. MBoC | ARTICLE Centrosome-nuclear axis repositioning drives the assembly of a bipolar spindle scaffold to ensure mitotic fidelity ABSTRACT During the initial stages of cell division, the cyto...

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