The 2016 revision of the World Health Organization classification of lymphoid neoplasms

Archive ouverte

Swerdlow, Steven H. | Campo, Elias | Pileri, Stefano A. | Harris, Nancy Lee | Stein, Harald | Siebert, Reiner | Advani, Ranjana | Ghielmini, Michele | Salles, Gilles A. | Zelenetz, Andrew D. | Jaffe, Elaine S.

Edité par CCSD ; American Society of Hematology -

International audience. A revision of the nearly 8-year-old World Health Organization classification of the lymphoid neoplasms and the accompanying monograph is being published. It reflects a consensus among hematopathologists, geneticists, and clinicians regarding both updates to current entities as well as the addition of a limited number of new provisional entities. The revision clarifies the diagnosis and management of lesions at the very early stages of lymphomagenesis, refines the diagnostic criteria for some entities, details the expanding genetic/molecular landscape of numerous lymphoid neoplasms and their clinical correlates, and refers to investigations leading to more targeted therapeutic strategies. The major changes are reviewed with an emphasis on the most important advances in our understanding that impact our diagnostic approach, clinical expectations, and therapeutic strategies for the lymphoid neoplasms

Consulter en ligne

Suggestions

Du même auteur

The International Consensus Classification of Mature Lymphoid Neoplasms: A Report from the Clinical Advisory Committee.

Archive ouverte | Campo, Elias | CCSD

International audience. Since the publication of the Revised European-American Classification of Lymphoid Neoplasms in 1994, subsequent updates of the classification of lymphoid neoplasms have been generated through...

Expansion of PD1-positive T Cells in Nodal Marginal Zone Lymphoma: A Potential Diagnostic Pitfall

Archive ouverte | Egan, Caoimhe | CCSD

International audience. The diagnosis of nodal marginal zone lymphoma (NMZL) can be challenging, with the differential diagnosis including other low-grade B-cell lymphomas, reactive hyperplasia, and even some cases ...

BCL3 rearrangements in B-cell lymphoid neoplasms occur in two breakpoint clusters associated with different diseases

Archive ouverte | Carbo-Meix, Anna | CCSD

International audience. The t(14;19)(q32;q13) often juxtaposes BCL3 with immunoglobulin heavy chain (IGH) resulting in overexpression of the gene. In contrast to other oncogenic translocations, BCL3 rearrangement (B...

Chargement des enrichissements...