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Clinical relevance of the study of hepatitis B virus covalently closed circular DNA

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Kumar, R. | Perez-Del-Pulgar, S. | Testoni, B. | Lebosse, F. | Zoulim, F.

Edité par CCSD ; Wiley-Blackwell -

International audience. Hepatitis B virus (HBV) remains a public health concern with 240 million people affected worldwide. HBV is an hepadnavirus that replicates its genome in hepatocytes. One of the key steps of the viral life cycle is the formation of ccc

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