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Granulocyte microvesicles with a high plasmin generation capacity promote clot lysis and improve outcome in septic shock

Archive ouverte | Cointe, Sylvie | CCSD

International audience. Abstract Microvesicles (MVs) have previously been shown to exert profibrinolytic capacity, which is increased in patients with septic shock (SS) with a favorable outcome. We, therefore, hypot...

Microparticles and Fibrinolysis

Archive ouverte | Vallier, Loris | CCSD

International audience. Microparticles (MPs) are submicronic vesicles which are formed by budding of the cellular membrane of virtually any cell type in response to cell activation or apoptosis. Both circulating MPs...

Maintenance chemotherapy in children with ALL exerts metronomic-like thrombospondin-1 associated anti-endothelial effect

Archive ouverte | Andre, Nicolas | CCSD

International audience. Maintenance chemotherapy is an important part of the treatment of ALL in children. It relies on the long-term oral administration of daily low-dose mercaptopurin and weekly low-dose methotrex...

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