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Increased serum levels of fractalkine and mobilisation of CD34+CD45− endothelial progenitor cells in systemic sclerosis

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Benyamine, Audrey | Magalon, Jeremy | Cointe, Sylvie | Lacroix, Romaric | Arnaud, Laurent | Bardin, Nathalie | Rossi, Pascal | Frances, Yves | Bernard-Guervilly, Fanny | Kaplanski, Gilles | Harlé, Jean-Robert | Weiller, Pierre-Jean | Berbis, Philippe | Braunstein, David | Jouve, Elisabeth | Lesavre, Nathalie | Couranjou, Françoise | Dignat-George, Francoise | Sabatier, Florence | Paul, Pascale | Granel, Brigitte

Edité par CCSD ; BioMed Central -

International audience. Background: The disruption of endothelial homeostasis is a major determinant in the pathogenesis of systemic sclerosis (SSc) and is reflected by soluble and cellular markers of activation, injury and repair. We aimed to provide a combined assessment of endothelial markers to delineate specific profiles associated with SSc disease and its severity.

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