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Peroxisome Proliferator–activated Receptors α and γ Down-regulate Allergic Inflammation and Eosinophil Activation

Archive ouverte | Woerly, Gaetane | CCSD

International audience. Allergic asthma is characterized by airway hyperresponsiveness, eosinophilia, and mucus accumulation and is associated with increased IgE concentrations. We demonstrate here that peroxisome p...

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Archive ouverte | Legrand, Fanny | CCSD

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Archive ouverte | Driss, Virginie | CCSD

International audience. Peripheral blood and tissue eosinophilia are a prominent feature in allergic diseases and during helminth infections. Eosinophil recruitment also frequently occurs upon mycobacterial infectio...

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