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Methyl donor deficiency affects fetal programming of gastric ghrelin cell organization and function in the rat

Archive ouverte | Bossenmeyer-Pourié, Carine | CCSD

Methyl donor deficiency (MDD) during pregnancy influences intrauterine development. Ghrelin is expressed in the stomach of fetuses and influences fetal growth, but MDD influence on gastric ghrelin is unknown. We examined the gastr...

Homocysteinylation of neuronal proteins contributes to folate deficiency-associated alterations of differentiation, vesicular transport, and plasticity in hippocampal neuronal cells.

Archive ouverte | Akchiche, Nassila | CCSD

International audience. Despite the key role in neuronal development of a deficit in the methyl donor folate, little is known on the underlying mechanisms. We therefore studied the consequences of folate deficiency ...

Early methyl donor deficiency produces severe gastritis in mothers and offspring through N -homocysteinylation of cytoskeleton proteins, cellular stress, and inflammation

Archive ouverte | Bossenmeyer-Pourié, Carine | CCSD

International audience. We examined the gastric mucosa structure and inflammatory status in control well-nourished Wistar dams and in Wistar dams deprived of choline, folate, and vitamin B12 during gestation and suc...

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