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The crystal structures of the binding domains of L- and H-ficolins provide insight into their recognition versatility

Archive ouverte | Garlatti, Virginie | CCSD

International audience

Carbohydrate recognition properties of human ficolins: glycan array screening reveals the sialic acid binding specificity of M-ficolin.

Archive ouverte | Gout, Evelyne | CCSD

International audience. Ficolins are oligomeric innate immune recognition proteins consisting of a collagen-like region and a fibrinogen-like recognition domain that bind to pathogen- and apoptotic cell-associated m...

The serine protease domain of MASP-3: enzymatic properties and crystal structure in complex with ecotin.

Archive ouverte | Gaboriaud, Christine | CCSD

International audience. Mannan-binding lectin (MBL), ficolins and collectin-11 are known to associate with three homologous modular proteases, the MBL-Associated Serine Proteases (MASPs). The crystal structures of t...

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