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The pluripotent genome in three dimensions is shaped around pluripotency factors

Archive ouverte | de Wit, Elzo | CCSD

International audience

Genomic matrix attachment region and chromosome conformation capture quantitative real time PCR assays identify novel putative regulatory elements at the imprinted Dlk1/Gtl2 locus

Archive ouverte | Braem, Caroline | CCSD

We previously showed that genomic imprinting regulates matrix attachment region activities at the mouse Igf2 (insulin-like growth factor 2) locus and that these activities are functionally linked to neighboring differentially meth...

Modulated contact frequencies at gene-rich loci support a statistical helix model for mammalian chromatin organization.

Archive ouverte | Court, Franck | CCSD

International audience. ABSTRACT: BACKGROUND: Despite its critical role for mammalian gene regulation, the basic structural landscape of chromatin in living cells remains largely unknown within chromosomal territori...

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