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All-oral daclatasvir plus asunaprevir for hepatitis C virus genotype 1b: a multinational, phase 3, multicohort study

Archive ouverte | Manns, Michael | CCSD

International audience. BackgroundAn unmet need exists for interferon-free and ribavirin-free treatments for chronic hepatitis C virus (HCV) infection. In this study, we assessed all-oral therapy with daclatasvir (N...

Ledipasvir and Sofosbuvir for Untreated HCV Genotype 1 Infection

Archive ouverte | Afdhal, Nezam | CCSD

International audience. BackgroundIn phase 2 studies, treatment with the all-oral combination of the nucleotide polymerase inhibitor sofosbuvir and the NS5A inhibitor ledipasvir resulted in high rates of sustained v...

The Case for Simplifying and Using Absolute Targets for Viral Hepatitis Elimination Goals

Archive ouverte | Foster, Graham | CCSD

International audience

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