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Characterization and localization of cocaine- and amphetamine-regulated transcript (CART) binding sites

Archive ouverte | Keller, Patrick | CCSD

International audience. Cocaine- and amphetamine-regulated transcript (CART) is widely expressed in the brain and various endocrine tissues. CART is implicated in many physiological functions including food intake, ...

[Feeding disorders in 5-HT4 receptor knockout mice].

Archive ouverte | Compan, Valerie | CCSD

International audience. To study the functional contributions of the 5-HT4 receptor subtype of serotonin (5-HT), we have generated knockout mice lacking the 5-HT4 receptor gene. The male mutant mice exhibit a hypose...

Adaptive changes in serotonin neurons of the raphe nuclei in 5-HT(4) receptor knock-out mouse

Archive ouverte | Conductier, Grégory | CCSD

Decreased serotonin (5-HT) transmission is thought to underlie several mental diseases, including depression and feeding disorders. However, whether deficits in genes encoding G protein-coupled receptors may down-regulate the acti...

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