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Continuation versus discontinuation of first-line chemotherapy in patients with metastatic squamous cell oesophageal cancer: A randomised phase II trial (E-DIS)

Archive ouverte | Adenis, Antoine | CCSD

International audience. PURPOSE:The role of chemotherapy has not been established in the treatment of metastatic squamous cell oesophageal cancer (mESCC).PATIENTS AND METHODS:E-DIS is a discontinuation trial, aimed ...

Sorafenib and irinotecan (NEXIRI) as second- or later-line treatment for patients with metastatic colorectal cancer and KRAS-mutated tumours: a multicentre Phase I/II trial

Archive ouverte | Samalin, E. | CCSD

IMPACT: 5.922. International audience. BACKGROUND: This trial evaluated the feasibility and efficacy of combined sorafenib and irinotecan (NEXIRI) as second- or later-line treatment of patients with KRAS-mutated met...

Tumor lymphocyte immune response to preoperative radiotherapy in locally advanced rectal cancer: The LYMPHOREC study

Archive ouverte | Mirjolet, C. | CCSD

IF 7.719 . International audience. Introduction: Some studies have suggested that baseline tumor-infiltrating-lymphocytes (TILs), such as CD8+ and FoxP3+ T-cells, may be associated with a better prognosis in colorec...

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