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The Role of Hepatic AMPK in Metabolic Adaptation under High-Protein Diet

Archive ouverte | Chalvon-Demersay, Tristan | CCSD

WOS:000361722702131. International audience. High protein diets are recognized to reduce food intake and body fat gain. As hepatic AMPK is involved in the transduction of both amino acid signals and energy sensing, ...

Role of liver AMPK and GCN2 kinases in the control of postprandial protein metabolism in response to mid-term high or low protein intake in mice

Archive ouverte | Chalvon-Demersay, Tristan | CCSD

International audience. AbstractPurposeProtein synthesis and proteolysis are known to be controlled through mammalian target of rapamycin, AMP-activated kinase (AMPK) and general control non-derepressible 2 (GCN2) p...

Low-protein diet induces, whereas high-protein diet reduces hepatic FGF21 production in mice, but glucose and not amino acids up-regulate FGF21 in cultured hepatocytes

Archive ouverte | Chalvon-Demersay, Tristan | CCSD

WOS:000385213000006. International audience. Fibroblast growth factor 21 (FGF21) is a polypeptide secreted by the liver and involved in several metabolic processes such as thermogenesis and lipid oxidation. The nutr...

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