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Introducing the outbreak threshold in epidemiology

Archive ouverte | Hartfield, Matthew | CCSD

International audience. When a pathogen is rare in a host population, there is a chance that it will die out because of stochastic effects instead of causing a major epidemic. Yet no criteria exist to determine when...

Clinical applications of pathogen phylogenies

Archive ouverte | Hartfield, Matthew | CCSD

International audience. Innovative sequencing techniques now allow the routine access of whole genomes of pathogens, generating vast amounts of data. Phylogenetic trees are a common method for synthesizing this info...

Evidence that hepatitis C virus genome partly controls infection outcome

Archive ouverte | Hartfield, Matthew | CCSD

International audience. Infection by hepatitis C virus (HCV) leads to one of two outcomes; either the infection resolves within approximately 6 months or the virus can persist indefinitely. Host genetics are known t...

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