Strategies evaluation in environmental conditions by symbolic data analysis: application in medicine and epidemiology to trachoma. . Strategies evaluation in environmental conditions by symbolic data analysis: application in medicine and epidemiology to trachoma. : Evaluation de stratégies de traitement dans certaines conditions environnementales: application en épidémiologie du trachome.

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Guinot, Christiane | Denis, Malvy | Jean-François, Schémann | Filipe, Afonso | Raja, Haddad | Diday, Edwin

Edité par CCSD ; Springer Verlag -

International audience. Trachoma, caused by repeated ocular infections with Chlamydia tra-chomatis whose vector is a y, is an important cause of blindness in the world. Weare presenting here an application of the Symbolic Data Analysis approach to aninterventional study on trachoma conducted in Mali. This study was conducted tochoose among three antibiotic strategies those with the best cost-eectiveness ra-tio and to nd the demographic and environmental parameters on which we couldtry to intervene. The Symbolic Data Analysis approach aims at studying classes ofindividuals considered as new units. These units are described by variables whichvalues express for each class the variation of the values taken by each of its indi-viduals. Finally, the results obtained are compared to those previously providedby multiple logistic regression analysis. Symbolic Data Analysis actually providesa new perspective on this study and suggests that some demographic, economicsand environmental parameters are related to the disease and its evolution duringthe treatment, whatever the strategy. Moreover, it is shown that the eciency ofeach strategy depends on environmental parameters.

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