Classification of human chromosome 21 gene-expression variations in down syndrome: Impact on disease phenotypes

Archive ouverte | Aït Yahya-Graison, E. | CCSD

Down syndrome caused by chromosome 21 trisomy is the most common genetic cause of mental retardation in humans. Disruption of the phenotype is thought to be the result of gene-dosage imbalance. Variations in chromosome 21 gene exp...

Selection of oligonucleotides for whole-genome microarrays with semi-automatic update.

Archive ouverte | Golfier, G. | CCSD

Two sequence-ready contigs spanning the two copies of a 200-kb duplication on human 21q: Partial sequence and polymorphisms

Archive ouverte | Potier, M. C. | CCSD

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