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Can we predict the influence of inflammation on voriconazole exposure? An overview

Archive ouverte | Boglione-Kerrien, Christelle | CCSD

International audience. Voriconazole is a triazole antifungal indicated for invasive fungal infections that exhibits a high degree of inter-individual and intra-individual pharmacokinetic variability. Voriconazole p...

A biological pharmacology network to secure the risk of drug–drug interaction with nirmatrelvir/ritonavir

Archive ouverte | Lemaitre, Florian | CCSD

International audience. Nirmatrelvir/ritonavir is a protease inhibitor antiviral drug indicated in the treatment of severe acute respiratory syndrome coronavirus-2 infections in high-risk patients for a severe disea...

Contribution of voriconazole N-oxide plasma concentration measurements to voriconazole therapeutic drug monitoring in patients with invasive fungal infection

Archive ouverte | Boglione-Kerrien, Christelle | CCSD

International audience. BACKGROUND: Voriconazole (VRC), a widely used triazole antifungal, exhibits significant inter- and intra-individual pharmacokinetic variability. The main metabolite voriconazole N-oxide (NOX)...

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