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Variations in Cellular Responses of Mouse T Cells to Adenosine-5'-Triphosphate Stimulation Do Not Depend on P2X7 Receptor Expression Levels but on Their Activation and Differentiation Stage

Archive ouverte | Safya, Hanaa | CCSD

International audience. A previous report has shown that regulatory T cells (Treg) were markedly more sensitive to adenosine-5'-triphosphate (ATP) than conventional T cells (Tconv). Another one has shown that Tregs ...

Hypercholesterolemia Negatively Regulates P2X7-Induced Cellular Function in CD4+ and CD8+ T-Cell Subsets from B6 Mice Fed a High-Fat Diet

Archive ouverte | Hutteau-Hamel, Tom | CCSD

International audience. We have previously showed that plasma membrane cholesterol and GM1 ganglioside content are responsible for the opposite sensitivity of mouse leukemic T cells to ATP. We also reported that the...

Androgens show sex-dependent differences in myelination in immune and non-immune murine models of CNS demyelination. Les androgènes montrent des effets dépendant du sexe dans des modèles murins immuns et non immuns de démyélinisation du système nerveux central

Archive ouverte | Zahaf, Amina | CCSD

International audience. Abstract Neuroprotective, anti-inflammatory, and remyelinating properties of androgens are well-characterized in demyelinated male mice and men suffering from multiple sclerosis. However, and...

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