Afficher la couverture 'Configurational fluctuations and flavin-substrate interactions in the flavoenzyme ThyX studied by time- and spectrally resolved fluorescence | Laptenok, Sergey, P.' en grand format
/5

0 avis

Configurational fluctuations and flavin-substrate interactions in the flavoenzyme ThyX studied by time- and spectrally resolved fluorescence

Archive ouverte

Laptenok, Sergey, P. | Bouzhir-Sima, Latifa | Myllykallio, Hannu | Liebl, Ursula | Vos, Marten, H.

Edité par CCSD ; EDP Sciences -

International audience. Femtosecond-resolved fluorescence of bacterial thymidilate synthase using a Kerr-gate based setup identifies a close-by tyrosine involved in flavin fluorescence quenching, shows that the substrate dUMP acts as a strong quencher itself and highlights functional configurational flexibility. © Owned by the authors, published by EDP Sciences, 2013

Suggestions

Du même auteur

Ultrafast real-time visualization of active site flexibility of flavoenzyme thymidylate synthase ThyX.

Archive ouverte | Laptenok, Sergey, P. | CCSD

International audience. In many bacteria the flavoenzyme thymidylate synthase ThyX produces the DNA nucleotide deoxythymidine monophosphate from dUMP, using methylenetetrahydrofolate as carbon donor and NADPH as hyd...

Intracellular dynamics of archaeal FANCM homologue Hef in response to halted DNA replication.

Archive ouverte | Lestini, Roxane | CCSD

International audience. Hef is an archaeal member of the DNA repair endonuclease XPF (XPF)/Crossover junction endonuclease MUS81 (MUS81)/Fanconi anemia, complementation group M (FANCM) protein family that in eukaryo...

Structural and functional insight into serine hydroxymethyltransferase from Helicobacter pylori

Archive ouverte | Sodolescu, Andreea | CCSD

International audience

Chargement des enrichissements...