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Relevance of ethylglucuronide as a marker of alcohol consumption : Development of dosage methods and study of factors potentially affecting its production

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Al Saabi, Alaa

Edité par CCSD -

Thèse en co-tutelle. Directeurs de thèse : Dr Nicolas Picard, Mme Delphine Allorgue

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Intérêt de l'Ethylglucuronide comme marqueur d'alcoolisation : développement de méthodes de dosage et étude des sources de variabilité de sa production. Relevance of Ethylglucuronide as a marker of alcohol consumption : development of dosage methods and study of factors potentially affecting its production

Archive ouverte | Al Saabi, Alaa | CCSD

Alcohol abuse is frequently associated with an increased risk of road accidents and violence, and can also lead to serious social and health problems. Therefore, the use of reliable markers to detect excessive punctual and/or chro...

Involvement of UDP-glucuronosyltransferases UGT1A9 and UGT2B7 in Ethanol Glucuronidation, and Interactions with Common Drugs of Abuse.

Archive ouverte | Al Saabi, Alaa | CCSD

International audience. Background: Ethylglucuronide (EtG) determination is increasingly used in clinical and forensic toxicology to document ethanol consumption. The enzymes involved in EtG production, as well as p...

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