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High rate of TNFRSF14 gene alterations related to 1p36 region in de novo follicular lymphoma and impact on prognosis.

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Launay, E. | Pangault, Céline | Bertrand, Pierre | Jardin, F. | Lamy, Thierry | Tilly, H. | Tarte, Karin | Bastard, C. | Fest, Thierry

Edité par CCSD ; Springer Nature -

International audience. Follicular lymphoma (FL) is characterized by the balanced chromosomal translocation t(14;18)(q32;q21) in about 80-90% of the cases. This primary event is not sufficient for emergence of FL, and acquisition of secondary genetic alterations is necessary to full disease manifestation.

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