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DEAD-box proteins, like Leishmania eIF4A, modulate interleukin (IL)-12, IL-10 and tumour necrosis factor-alpha production by human monocytes.

Archive ouverte | Barhoumi, M. | CCSD

International audience. Previously we showed that His-tagged, recombinant, Leishmania infantum eukaryotic initiation factor (LeIF) was both an RNA-dependent ATPase and an ATP-dependent RNA helicase in vitro, as desc...

Analyses of the functional regions of DEAD-box RNA helicases with deletion and chimera constructs tested in vivo and in vitro

Archive ouverte | Banroques, J. | CCSD

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Motif III in superfamily 2 "helicases" helps convert the binding energy of ATP into a high affinity RNA binding site in the yeast DEAD-box protein Ded1

Archive ouverte | Banroques, J. | CCSD

International audience

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