On differentiation and homeostatic behaviours of Boolean dynamical systems

Archive ouverte

Remy, Elisabeth | Ruet, Paul

Edité par CCSD -

International audience. We study rules proposed by the biologist R. Thomas relating the structure of a concurrent system of interacting genes (represented by a signed directed graph called a regulatory graph) with its dynamical properties. We prove that the results in [10] are stable under projection, and this enables us to relax the assumptions under which they are valid. More precisely, we relate here the presence of a positive (resp. negative) circuit in a regulatory graph to a more general form of biological differentiation (resp. of homeostasis).

Suggestions

Du même auteur

Graphic requirements for multistability and attractive cycles in a Boolean dynamical framework

Archive ouverte | Remy, Elisabeth | CCSD

International audience. To each Boolean function f : {0, 1}^n → {0, 1}^n and each x ∈ {0, 1}^n, we associate a signed directed graph G(x), and we show that the existence of a positive circuit in G(x) for some x is a...

From minimal signed circuits to the dynamics of Boolean regulatory networks

Archive ouverte | Remy, Elisabeth | CCSD

International audience. It is acknowledged that the presence of positive or negative circuits in regulatory networks such as genetic networks is linked to the emergence of significant dynamical properties such as mu...

From multivalued to Boolean functions: preservation of soft nested canalization

Archive ouverte | Remy, Élisabeth | CCSD

Nested canalization (NC) is a property of Boolean functions which has been recently extended to multivalued functions. We study the effect of the Van Ham mapping (from multivalued to Boolean functions) on this property. We introdu...

Chargement des enrichissements...