Rôle des lymphocytes NKT invariants (iNKT) dans la réponse granulomateuse hépatique à l'infection par Leishmania donovani

Archive ouverte | Drogoul, Anne Sophie | CCSD

Invariant NKT lymphocytes and granuloma formation in the liver in response to Leishmania donovani infection

Archive ouverte | Robert-Gangneux, Florence | CCSD

Invariant NKT cells drive hepatic cytokinic microenvironment favoring efficient granuloma formation and early control of Leishmania donovani infection.

Archive ouverte | Robert-Gangneux, Florence | CCSD

International audience. The development of inflammatory granulomas around infected Kupffer cells is necessary for hepatic parasite clearance during visceral leishmaniasis. Invariant NKT (iNKT) cells are predominant ...