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Molecular Characterization of Non-B HIV Type 1 Isolates from Patients of a Department of Infectious Diseases, University Hospital of Bordeaux, France, 1989-2009.

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Javaugue, François-Charles | Recordon-Pinson, Patricia | Decoin, Madeleine | Masquelier, Bernard | Cazanave, Charles | Neau, Didier | Dupon, Michel | Ragnaud, Jean-Marie | Fleury, Hervé J

Edité par CCSD ; Mary Ann Liebert -

International audience. Abstract The molecular characterization of non-B HIV type 1 subtypes and the sociodemographic baseline characteristics have been studied for 114 non-B HIV-1-infected patients followed at the University Hospital of Bordeaux, France, and diagnosed as HIV infected between 1989 and 2009. Individuals enrolled in this study were mainly women with heterosexual transmission in West and Central Africa and who have been discovered to be HIV positive during pregnancy. Nevertheless, HIV acquisition among individuals born in France was significantly increasing. Recombinant form CRF02_AG was the most frequent subtype (38%) among a highly diverse viral background since 19 subtypes and CRFs have been characterized with a maximal diversity observed in the past decade.

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