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Application of Hybrid Models to Blood Cell Production in the Bone Marrow

Archive ouverte | Bessonov, Nikolai | CCSD

International audience. A hybrid model of red blood cell production, where cells are considered as discrete objects while intra-cellular proteins and extra-cellular biochemical substances are described with continuo...

Dynamics of erythroid progenitors and erythroleukemia

Archive ouverte | Bessonov, Nikolai | CCSD

International audience. The paper is devoted to mathematical modelling of erythropoiesis, production of red blood cells in the bone marrow. We discuss intra-cellular regulatory networks which determine self-renewal ...

HYBRID MODEL OF ERYTHROPOIESIS AND LEUKEMIA TREATMENT WITH CYTOSINE ARABINOSIDE

Archive ouverte | Kurbatova, Polina | CCSD

International audience. A hybrid model of cell population dynamics, where cells are discrete elements whose dynamics depend on continuous intracellular and extracellular processes, is developed to simulate the evolu...

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