High intensity ultrasound clamp for bloodless partial nephrectomy: In vitro and in vivo experiments.

Archive ouverte

Lafon, Cyril | Bouchoux, Guillaume | Murat, François Joseph | Birer, Alain | Theillere, Yves | Chapelon, Jean Yves | Cathignol, Dominique

Edité par CCSD ; Elsevier -

International audience. In some patients at risk of disease recurrence of renal cancers, maximum conservation of the kidney is possible through partial nephrectomy. However, bloodless surgery is difficult to achieve. The article describes an ultrasonic clamp, which optimises energy deposition and monitors lesion development with an echo-based technique. Using this novel apparatus, coagulation necroses have been obtained in vitro on substantial thicknesses (23 to 38 mm) over exposure durations ranging from 10 s to 130 s, and with acoustic intensities of less than 15 W/cm(2) per transducer. When used for coagulation purposes, two transducers situated on opposite arms of the clamp are driven, while for monitoring, only one is used. Lesions are monitored in real time by analysing the echo signal returned by the opposite arm of the clamp. The presence of a lesion is evaluated on the basis of energy changes and echo phase as a function of time. Both kidneys of two pigs (30 to 36 mm thick) were treated in vivo with the clamp, and the partial nephrectomies performed proved to be bloodless.

Consulter en ligne

Suggestions

Du même auteur

Dual-mode ultrasound transducer for image-guided interstitial thermal therapy.

Archive ouverte | Bouchoux, Guillaume | CCSD

International audience. Deep-seated tumors can be treated by minimally invasive interstitial ultrasound thermal therapy. A miniature transducer emitting high-intensity acoustic waves is placed in contact with the ta...

Delivery by shock waves of active principle embedded in gelatin-based capsules.

Archive ouverte | Goldenstedt, Cedric | CCSD

International audience. PURPOSE: Delivering a drug close to the targeted cells improves its benefit versus risk ratio. A possible method for local drug delivery is to encapsulate the drug into solid microscopic carr...

Study of a dual-mode array integrated in a multi-element transducer for imaging and therapy of prostate cancer

Archive ouverte | Mari, Jean-Martial | CCSD

International audience. The development of endocavitary dual-mode probes is essential for the accurate treatment of many deep seated cancers which require a high imaging resolution and the capacity to selectively tr...

Chargement des enrichissements...