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Remodeling of the neuromuscular junction in mice with deleted exons 5 and 6 of acetylcholinesterase.

Archive ouverte | Girard, Emmanuelle | CCSD

At the vertebrate skeletal neuromuscular junction (NMJ), two closely related enzymes can hydrolyze acetylcholine (ACh): acetylcholinesterase (AChE) and butyrylcholinesterase (BChE). Advances in mouse genomics offer new approaches ...

Distinct localization of collagen Q and PRiMA forms of acetylcholinesterase at the neuromuscular junction

Archive ouverte | Bernard, Véronique | CCSD

International audience. Acetylcholinesterase (AChE) terminates the action of acetylcholine at cholinergic synapses thereby preventing rebinding of acetylcholine to nicotinic postsynaptic receptors at the neuromuscul...

Contributions of selective knockout studies to understanding cholinesterase disposition and function

Archive ouverte | Camp, Shelley | CCSD

International audience. The complete knockout of the acetylcholinesterase gene (AChE) in the mouse yielded a surprising phenotype that could not have been predicted from deletion of the cholinesterase genes in Droso...

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