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HPr kinase/phosphorylase, a Walker motif A-containing bifunctional sensor enzyme controlling catabolite repression in Gram-positive bacteria

Archive ouverte | Poncet, Sandrine | CCSD

International audience. Carbon catabolite repression (CCR) in Gram-positive bacteria is regulated by the bifunctional enzyme HPr kinase/phosphorylase (HprK/P). This enzyme catalyses the ATP- as well as the pyrophosp...

Structural analysis of the bacterial HPr kinase/phosphorylase V267F mutant gives insights into the allosteric regulation mechanism of this bifunctional enzyme.

Archive ouverte | Chaptal, Vincent | CCSD

International audience. The HPr kinase/phosphorylase (HPrK/P) is a bifunctional enzyme that controls the phosphorylation state of the phosphocarrier protein HPr, which regulates the utilization of carbon sources in ...

X-ray structure of a domain-swapped dimer of Ser46-phosphorylated Crh from Bacillus subtilis

Archive ouverte | Chaptal, Vincent | CCSD

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