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In Xenopus egg extracts DNA replication initiates preferentially at or near asymmetric AT sequences.

Archive ouverte | Stanojcic, S. | CCSD

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Archive ouverte | Lemaitre, Jm | CCSD

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A spontaneous Cdt1 mutation in 129 mouse strains reveals a regulatory domain restraining replication licensing

Archive ouverte | Coulombe, P. | CCSD

International audience. Cdt1 is required for loading the replicative DNA helicase MCM2/7, a process known as DNA replication licensing. Here we show that 129 mouse strains express a Cdt1 mutated allele with enhanced...

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