Evolution of viral proteins [chap.12]

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Koonin, Eugene V. | Krupovic, Mart

Edité par CCSD ; Wolters Kluwer -

International audience. CONTENTSIntroductionVirus hallmark proteinsRNA-dependent RNA polymerase and reverse transcriptaseFamily B DNA polymerasesRolling circle replication initiation endonucleasesPalm/RRM domain, the core of the virus replication machineryHelicases and genome packaging NTPasesSuperfamily 3 helicasesLarge terminase subunitFtsK-like genome packaging ATPaseVirus capsid proteinsSingle jelly roll capsid proteinDouble jelly roll capsid proteinsHK97 capsid proteinsEvolutionary roots of the virus hallmark proteins and implications for the origin of virusesModerately conserved proteins involved in core virus functionsP-loop enzymesProteasesDNA-dependent RNA polymerases and transcription factorsCapping enzymesLineage-specific virus proteins involved in core processesVirus proteins involved in virus-host interactionsDark matter of virus proteomesExaptation and recruitment of host proteins as major routes of virus protein evolutionConcluding remarks: organization of the virus pan-proteome and challenges in its analysis

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