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Development and validation of serological markers for detecting recent Plasmodium vivax infection

Archive ouverte | Longley, Rhea, J | CCSD

International audience. A major gap in the Plasmodium vivax elimination toolkit is the identification of individuals carrying clinically silent and undetectable liver-stage parasites, called hypnozoites. This study ...

Identification of highly-protective combinations of Plasmodium vivax recombinant proteins for vaccine development

Archive ouverte | França, Camila Tenorio | CCSD

International audience. The study of antigenic targets of naturally-acquired immunity is essential to identify and prioritize antigens for further functional characterization. We measured total IgG antibodies to 38 ...

Developing sero-diagnostic tests to facilitate Plasmodium vivax Serological Test-and-Treat approaches: modeling the balance between public health impact and overtreatment

Archive ouverte | Obadia, Thomas | CCSD

International audience. Background Eliminating Plasmodium vivax will require targeting the hidden liver-stage reservoir of hypnozoites. This necessitates new interventions balancing the benefit of reducing vivax tra...

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