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Evidence of Lymphocytic Choriomeningitis Virus (LCMV) in Domestic Mice in Gabon: Risk of Emergence of LCMV Encephalitis in Central Africa

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N′dilimabaka, Nadine | Berthet, Nicolas | Rougeron, Virginie | Mangombi, Joa Braïthe | Patrick, Durand | Maganga, Gael | Bouchier, Christiane | Schneider, Bradley | Fair, Joseph | Renaud, François | Leroy, Eric, M.

Edité par CCSD ; American Society for Microbiology -

International audience. ABSTRACT Lymphocytic choriomeningitis virus (LCMV) can cause acute fatal disease on all continents but was never detected in Africa. We report the first detection of LCMV RNA in a common European house mouse ( Mus musculus domesticus ) in Africa. Phylogenetic analyses show a close relationship with North American strains. These findings suggest that there is a risk of the appearance of LCMV acute encephalitis cases. This is a perfect example of virus dissemination by its natural host that may have dramatic public health consequences.

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