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Transversal sero-epidemiological study of Bordetella pertussis in Tehran, Iran

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Noel, Gaelle | Badmasti, Farzad | Nikbin, Vajihe | Zahraei, Seyed | Madec, Yoann | Tavel, David | Ait-Ahmed, Mohand | Guiso, Nicole | Shahcheraghi, Fereshteh | Taieb, Fabien

Edité par CCSD ; Public Library of Science -

International audience. Pertussis remains endemic despite high vaccine coverage in infants and toddlers. Pertussis vaccines confer protection but immunity wanes overtime and boosters are needed in a lifetime. Iran, eligible for the Expanded Program on Immunization that includes the primary immunization, implemented two additional booster doses using a whole-cell vaccine (wPV) at 18 months-old and about 6 years-old. Duration of protection induced by the wPVs currently in use and their impact as pre-school booster are not well documented. This study aimed at assessing vaccination compliance and at estimating the duration of protection conferred by vaccination with wPV in children aged < 15 years in Tehran, Iran.

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