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Chromosome instability in human hepatocellular carcinoma depends on p53 status and aflatoxin exposure

Archive ouverte | Pineau, Pascal | CCSD

International audience. Hepatocellular carcinoma (HCC) is a heterogeneous disease triggered by various risk factors and frequently characterized by chromosome instability. This instability is considered to be caused...

A t(3;8) chromosomal translocation associated with hepatitis B virus intergration involves the carboxypeptidase N locus

Archive ouverte | Pineau, Pascal | CCSD

International audience. Integrated hepatitis B virus (HBV) DNA is found in the great majority of human hepatocellular carcinomas, suggesting that these viral integrations may be implicated in liver oncogenesis. Besi...

Distinct chromosomal abnormality pattern in primary liver cancer of non-B, non-C patients

Archive ouverte | Marchio, Agnès | CCSD

International audience. To discriminate among the chromosomal abnormalities associated with the etiology of hepatocellular carcinoma (HCC), we performed a comparative genomic hybridization (CGH) analysis on 34 HCCs ...

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