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Legionella pneumophila Modulates Mitochondrial Dynamics to Trigger Metabolic Repurposing of Infected Macrophages

Archive ouverte | Escoll, Pedro | CCSD

International audience. The intracellular bacteria Legionella pneumophila encodes a type IV secretion system (T4SS) that injects effector proteins into macrophages in order to establish and replicate within the Legi...

Manipulation of Autophagy by Bacterial Pathogens Impacts Host Immunity

Archive ouverte | Kunz, Tobias | CCSD

International audience. Autophagy is a highly conserved catabolic process, degrading unnecessary or damaged components in the eukaryotic cell to maintain cellular homeostasis, but it is also an intrinsic cellular de...

Hiding in the yolk: A unique feature of Legionella pneumophila infection of zebrafish

Archive ouverte | Viana, Flávia | CCSD

International audience. The zebrafish has become a powerful model organism to study host-pathogen interactions. Here, we developed a zebrafish model to dissect the innate immune response to Legionella pneumophila du...

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