Molecular epidemiology of merkel cell polyomavirus: evidence for geographically related variant genotypes.

Archive ouverte

Martel-Jantin, Claire | Filippone, Claudia | Tortevoye, Patricia | Afonso, Philippe V | Betsem, Edouard | Descorps-Declere, Stéphane | Nicol, Jérôme T J | Touzé, Antoine | Coursaget, Pierre | Crouzat, Maryse | Berthet, Nicolas | Cassar, Olivier | Gessain, Antoine

Edité par CCSD ; American Society for Microbiology -

International audience. Merkel cell polyomavirus (MCPyV) is linked to a cutaneous cancer mainly occurring in Caucasians. DNA from skin swabs of 255 adults, originating from the 5 continents, were subjected to MCPyV PCRs. Phylogenetic analyses demonstrate the existence of 5 major geographically related MCPyV genotypes (Europe/North America, Africa [sub-Saharan], Oceania, South America, and Asia/Japan).

Suggestions

Du même auteur

Merkel cell polyomavirus infection occurs during early childhood and is transmitted between siblings

Archive ouverte | Martel-Jantin, Claire | CCSD

International audience. Merkel cell polyomavirus (MCPyV) is thought to be the etiological agent of Merkel cell carcinoma, but little is known about its distribution and modes of transmission. We conducted seroepidem...

Trichodysplasia spinulosa polyomavirus infection occurs during early childhood with intra-familial transmission, especially from mother to child

Archive ouverte | Pedergnana, Vincent | CCSD

International audience. To get new insights into the distribution and modes of acquisition of trichodysplasia spinulosa polyomavirus (TSPyV) infection, we performed a seroepidemiological study in two populations fro...

Genetic variability and integration of Merkel cell polyomavirus in Merkel cell carcinoma.

Archive ouverte | Martel-Jantin, Claire | CCSD

International audience. Merkel cell polyomavirus (MCPyV) is associated to Merkel cell carcinoma (MCC). We studied 113 MCC tumoral skin lesions originating from 97 patients. MCPyV detection was higher in fresh-frozen...

Chargement des enrichissements...