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Bacterial flagellins: mediators of pathogenicity and host immune responses in mucosa.

Archive ouverte | Cruz Ramos, Hugo | CCSD

Flagella contribute to the virulence of pathogenic bacteria through chemotaxis, adhesion to and invasion of host surfaces. Flagellin is the structural protein that forms the major portion of flagellar filaments. Thus, flagellin co...

Compartmentalized Antimicrobial Defenses in Response to Flagellin

Archive ouverte | Vijayan, Aneesh | CCSD

International audience. Motility is often a pathogenicity determinant of bacteria targeting mucosal tissues. Flagella constitute the machinery that propels bacteria into appropriate niches. Besides motility, the str...

Mucosal interplay among commensal and pathogenic bacteria: lessons from flagellin and Toll-like receptor 5.

Archive ouverte | Rumbo, Martin | CCSD

International audience. Toll-like receptors (TLR) detect pathogen-associated molecular patterns (PAMP) and play a crucial role in triggering immunity. Due to their large surfaces in direct contact with the environme...

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