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Characterization of cell-fate decision landscapes by estimating transcription factor dynamics

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Jiménez, Sara | Schreiber, Valérie | Mercier, Reuben | Gradwohl, Gérard | Molina, Nacho

Edité par CCSD ; Cell Press Elsevier -

International audience. Highlights d FateCompass is an integrative pipeline to estimate TF activity dynamics d FateCompass learns trajectories using RNA velocity or a differentiation potential d FateCompass reveals known and novel regulators in pancreatic datasets d Lineage tracing validates FateCompass predictions for in vitro b cell differentiation

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