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Mega‐trials in heart failure: effects of dilution in examination of new therapies

Archive ouverte | Davison, Beth, A | CCSD

International audience. Aims: Over the last 30 years, many medicine development programmes in acute and chronic heart failure (HF) with preserved ejection fraction (HFpEF) have failed, in contrast to those in HF wit...

Is acute heart failure a distinctive disorder? An analysis from BIOSTAT‐CHF

Archive ouverte | Davison, Beth, A | CCSD

International audience. Aims: This retrospective analysis sought to identify markers that might distinguish between acute heart failure (HF) and worsening HF in chronic outpatients. Methods and Results: The BIOSTAT-...

Regional variation of effects of new antidiabetic medications in cardiovascular outcome trials

Archive ouverte | Cotter, Gad | CCSD

International audience. Background In international trials, glucagon-like protein-1 receptor agonists (GLP-1RAs) and sodium-glucose cotransporter-2 inhibitors (SGLT2Is) were effective in improving cardiovascular (CV...

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