Afficher la couverture 'Water-Soluble Aza-BODIPYs: Biocompatible Organic Dyes for High Contrast In Vivo NIR-II Imaging | Godard, Amélie' en grand format
/5

0 avis

Water-Soluble Aza-BODIPYs: Biocompatible Organic Dyes for High Contrast In Vivo NIR-II Imaging

Archive ouverte

Godard, Amélie | Kalot, Ghadir | Pliquett, Jacques | Busser, Benoit | Le Guével, Xavier | Wegner, K. David | Resch-Genger, Ute | Rousselin, Yoann | Coll, Jean-Luc | Denat, Franck | Bodio, Ewen | Goze, Christine | Sancey, Lucie

Edité par CCSD ; American Chemical Society -

International audience. A simple NIR-II emitting water-soluble system has been developed and applied in vitro and in vivo. In vitro, the fluorophore quickly accumulated in 2D and 3D cell cultures and rapidly reached the tumor in rodents, showing high NIR-II contrast for up to 1 week. This very efficient probe possesses all the qualities necessary for translation to the clinic as well as for the development of NIR-II emitting materials.

Suggestions

Du même auteur

NIR-II Aza-BODIPY Dyes Bioconjugated to Monoclonal Antibody Trastuzumab for Selective Imaging of HER2-Positive Ovarian Cancer

Archive ouverte | Godard, Amélie | CCSD

International audience. Using fluorescence guided surgery (FGS) to cytoreductive surgery helps achieving complete resection of microscopic ovarian tumors. The use of visible and NIR-I fluorophores has led to benefic...

Aza-BODIPY: A New Vector for Enhanced Theranostic Boron Neutron Capture Therapy Applications

Archive ouverte | Kalot, Ghadir | CCSD

International audience. Boron neutron capture therapy (BNCT) is a radiotherapeutic modality based on the nuclear capture of slow neutrons by stable 10 B atoms followed by charged particle emission that inducing exte...

Lipoprotein interactions with water-soluble NIR-II emitting aza-BODIPYs boost the fluorescence signal and favor selective tumor targeting

Archive ouverte | Kalot, Ghadir | CCSD

International audience. Following intravenous administration, the interaction of fluorescent exogenous molecules with circulating endogenous transporters can influence their photophysical properties as well as their...

Chargement des enrichissements...