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Chitin Synthases with a Myosin Motor-Like Domain Control the Resistance of Aspergillus fumigatus to Echinocandins

Archive ouverte | Jiménez-Ortigosa, Cristina | CCSD

International audience. Aspergillus fumigatus has two chitin synthases (CSMA and CSMB) with a myosin motor-like domain (MMD) arranged in a head-to-head configuration. To understand the function of these chitin synth...

Aspergillus fumigatus Cell Wall α-(1,3)-Glucan Stimulates Regulatory T-Cell Polarization by Inducing PD-L1 Expression on Human Dendritic Cells

Archive ouverte | Stephen-Victor, Emmanuel | CCSD

International audience

Circulating human basophils lack the features of professional antigen presenting cells

Archive ouverte | Sharma, Meenu | CCSD

International audience. Recent reports in mice demonstrate that basophils function as antigen presenting cells (APC). They express MHC class II and co-stimulatory molecules CD80 and CD86, capture and present soluble...

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