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Visualization of chemical modifications in the human 80S ribosome structure

Archive ouverte | Natchiar, S. Kundhavai | CCSD

Comment in RNA modifications: Ribosomes get decorated. [Nat Chem Biol. 2017]. International audience. Chemical modifications of human ribosomal RNA (rRNA) are introduced during biogenesis and have been implicated in...

Identification of Mg 2+ ions next to nucleotides in cryo-EM maps using electrostatic potential maps

Archive ouverte | Wang, Jimin | CCSD

International audience. Cryo electron microscopy (cryo-EM) can produce maps of macromolecules that have resolutions that are sufficiently high that structural details such as chemical modifications, water molecules ...

Focused classification and refinement in high-resolution cryo-EM structural analysis of ribosome complexes

Archive ouverte | von Loeffelholz, Ottilie | CCSD

International audience. Cryo electron microscopy (cryo-EM) historically has had a strong impact on the structural and mechanistic analysis of protein synthesis by the prokaryotic and eukaryotic ribosomes. Vice versa...

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