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Association of HLA-DRB1*09:01 with tIgE levels among African ancestry individuals with asthma

Archive ouverte | Vince, Nicolas | CCSD

International audience. BACKGROUND:Asthma is a complex chronic inflammatory disease of the airways. Association studies between HLA and asthma were first reported in the 1970's, and yet, the precise role of HLA alle...

Association study in African-admixed populations across the Americas recapitulates asthma risk loci in non-African populations

Archive ouverte | Daya, Michelle | CCSD

International audience. Asthma is a complex disease with striking disparities across racial and ethnic groups. Despite its relatively high burden, representation of individuals of African ancestry in asthma genomewi...

Easy-HLA, a validated web application suite to reveal the full details of HLA typing

Archive ouverte | Geffard, Estelle | CCSD

International audience. MOTIVATION:The HLA system plays a pivotal role in both clinical applications and immunology research. Typing HLA genes in patient and donor is indeed required in hematopoietic stem cell and s...

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