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Dok1 and Dok2 proteins regulate cell cycle in hematopoietic stem and progenitor cells . Dok1 and Dok2 proteins regulate cell cycle in hematopoietic stem and progenitor cells : Dok1 and Dok2 regulate HSPC cell cycle

Archive ouverte | Coppin, Emilie | CCSD

International audience. Dok1 and Dok2 proteins play a crucial role in myeloid cell proliferation as demonstrated by Dok1 and Dok2 gene inactivation, which induces a myeloproliferative disease in aging mice. In this ...

Selection of T-cell receptors with a recurrent CDR3β peptide-contact motif within the repertoire of alloreactive CD8(+) T cells.

Archive ouverte | Scifo, Caroline | CCSD

International audience. Peptide/MHC complexes recognized by alloreactive T lymphocytes (TLs) have been identified, but their contribution to in vivo allo-rejection is not known. We previously characterized the pepti...

Alternatively spliced NKp30 isoforms affect the prognosis of gastrointestinal stromal tumors.

Archive ouverte | Delahaye, Nicolas F | CCSD

International audience. The natural killer (NK) cell receptor NKp30 is involved in the recognition of tumor and dendritic cells (DCs). Here we describe the influence of three NKp30 splice variants on the prognosis o...

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