LC-MS/MS screen for xenobiotics and metabolites.

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Sauvage, François-Ludovic | Marquet, Pierre

Edité par CCSD ; Humana Press/Springer Imprint -

International audience. Liquid chromatography coupled to tandem mass spectrometry (LC-MS/MS) is now considered as a perfect complement to HPLC-DAD (diode array detection) and gas chromatography (GC)-MS for the general unknown screening of drugs and toxic compounds.Here we describe a procedure applied routinely in our laboratory for clinical and forensic applications using the QTRAP™ technology.

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