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Microtubule-associated Proteins 1 (MAP1) Promote Human Immunodeficiency Virus Type I (HIV-1) Intracytoplasmic Routing to the Nucleus

Archive ouverte | Fernandez, Juliette | CCSD

International audience. After cell entry, HIV undergoes rapid transport toward the nucleus using microtubules and microfilaments. Neither the cellular cytoplasmic components nor the viral proteins that interact to m...

Human nucleoporins promote HIV-1 docking at the nuclear pore, nuclear import and integration.

Archive ouverte | Di Nunzio, Francesca | CCSD

International audience. The nuclear pore complex (NPC) mediates nucleo-cytoplasmic transport of macromolecules and is an obligatory point of passage and functional bottleneck in the replication of some viruses. The ...

Transportin-1 binds to the HIV-1 capsid via a nuclear localization signal and triggers uncoating

Archive ouverte | Fernandez, Juliette | CCSD

International audience

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